BioRestorative Therapies Advances Stem Cell Treatments for Back Pain and Obesity

By Advos

TL;DR

BioRestorative Therapies, Inc. is inkling deals and securing patents to treat back pain and obesity, gaining a competitive advantage in the regenerative medicine industry.

BRTX-100 uses a patient’s stem cells, harvested, cultured, and then injected directly into the affected disc to start the repair process, providing a methodical approach to treating chronic lower back pain.

Stem cell-based therapies like BRTX-100 and ThermoStem aim to make the world a better place by providing regenerative treatments for prevalent conditions like chronic lower back pain and obesity.

New preliminary 26–52-week blinded data from the ongoing phase 2 clinical trial with BRTX-100 was presented at the ORS PSRS 7th International Spine Research Symposium, offering interesting insights into the potential of stem cell therapies.

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BioRestorative Therapies Advances Stem Cell Treatments for Back Pain and Obesity

BioRestorative Therapies, Inc. (NASDAQ: BRTX) is making substantial strides in the development of stem cell-based therapies for chronic lower back pain and obesity. The company recently presented preliminary data from its phase 2 clinical trial for BRTX-100, an autologous stem cell product designed to treat chronic lower back pain caused by degenerative discs.

The preliminary results, presented at the Orthopaedic Research Society (ORS) Philadelphia Spine Research Society (PSRS) 7th International Spine Research Symposium, showed promising trends in pain reduction and functional improvement. According to CEO Lance Alstodt, 70% of patients reported a significant increase in function and decrease in pain at the 26-week mark, indicating potential success in meeting the trial's efficacy endpoints.

In addition to BRTX-100, BioRestorative is advancing its ThermoStem program, which utilizes brown adipose-derived stem cells to target obesity and metabolic disorders. The company recently received a Notice of Allowance from the Israel Patent Office for a new patent application covering key aspects of its ThermoStem platform, marking its 14th international patent in this area.

Further expanding its capabilities, BioRestorative obtained a license from the New York State Department of Health to process, isolate, expand, and preserve allogeneic donor tissue, including stem cells, for medical research. This expanded license enables the company to develop a broader range of off-the-shelf cell-based biologic products.

These developments are significant for the 25 million Americans suffering from chronic lower back pain and the 40% of Americans who are obese. Current treatments for these conditions are often limited in effectiveness, and BioRestorative's stem cell therapies could potentially offer more targeted and regenerative solutions.

As BioRestorative continues to advance its clinical trials and expand its intellectual property portfolio, the company is positioning itself as a key player in the regenerative medicine field. The potential impact of these therapies on chronic pain management and obesity treatment could be substantial, offering new hope for millions of patients and potentially reshaping treatment approaches in these areas.

Curated from News Direct

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