Lantern Pharma Completes Successful Phase 1a Trial for AI-Developed Cancer Drug LP-184
TL;DR
Lantern Pharma's LP-184 Phase 1a success offers investors a competitive edge in oncology with a $15B market potential and advanced AI-driven drug development.
LP-184 demonstrated favorable safety and pharmacokinetics in 63 patients with advanced solid tumors, achieving 48% disease control at therapeutic doses using RADR AI platform.
This breakthrough brings hope for better cancer treatments, potentially improving survival and quality of life for patients with difficult-to-treat solid tumors worldwide.
Lantern Pharma's AI platform analyzed 200B data points to develop LP-184, showing promising antitumor activity in DDR-deficient cancers like NSCLC and colon cancer.
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Lantern Pharma Inc. (NASDAQ: LTRN) has successfully completed its Phase 1a clinical trial for LP-184, achieving all primary endpoints with a favorable safety profile and early signs of antitumor activity. The open-label study, conducted under clinical trial identifier NCT05933265, enrolled 63 patients with advanced relapsed or refractory solid tumors, including glioblastoma multiforme (GBM).
The trial results demonstrated disease control in 48% of evaluable patients at therapeutic dose levels, with particularly notable responses observed in DNA damage response (DDR)-deficient cancers. These included non-small cell lung cancer (NSCLC), colon cancer, thymic carcinoma, and gastrointestinal stromal tumors (GIST). The absence of dose-limiting toxicities and predominantly mild adverse events positions LP-184 as a promising therapeutic candidate for advanced cancer treatment.
Lantern Pharma's proprietary RADR® artificial intelligence platform played a crucial role in the drug's development, leveraging over 200 billion oncology-focused data points and more than 200 machine learning algorithms. This AI-driven approach has significantly accelerated the drug discovery process, potentially reducing both development timelines and costs traditionally associated with oncology drug development.
The company plans to advance LP-184 into Phase 1b and Phase 2 clinical studies, specifically targeting triple-negative breast cancer (TNBC), NSCLC, and other DDR-deficient cancers. This progression represents a critical milestone in the application of artificial intelligence to oncology drug development, potentially setting new standards for efficiency in cancer treatment research.
For investors and stakeholders seeking additional information, the company maintains updated news and developments available through their dedicated newsroom at https://ibn.fm/LTRN. The successful trial outcomes underscore the growing importance of AI-driven approaches in addressing complex medical challenges and accelerating the delivery of potentially life-changing therapies to cancer patients worldwide.
Curated from InvestorBrandNetwork (IBN)
