Sino Biological, Inc. (Shenzhen Stock Exchange: 301047.SZ), a global leader in recombinant technology, has announced the launch of its XPressMAX Cell-Free Protein Synthesis Kit (Cat#: CFKIT02). The kit is designed to accelerate artificial intelligence (AI)-powered high-throughput screening pipelines for antibody drug discovery by enabling rapid, in vitro production of target proteins and antibodies without the constraints of traditional cell-based expression systems.
The XPressMAX kit leverages advanced cell-free protein synthesis technology, based on an E. coli lysate fully supplemented with essential transcription and translation components. It allows direct protein synthesis from plasmid or PCR templates and supports the rapid expression and validation of VHH, scFv, Fab, and miniproteins. According to the company, the kit achieves synthesis in just three hours with a success rate greater than 99%, and supports complex disulfide bonding for native folding and bioactivity without additional enhancers.
By integrating with AI-powered screening platforms, XPressMAX aims to dramatically reduce development timelines and costs. Sino Biological has established a high-throughput cell-free expression platform that validates over 2,000 scFv/VHH molecules in three to four weeks, matching AI’s rapid iteration demands. Dr. Rob Burgess, Chief Business Officer at Sino Biological US, Inc., stated: "Our XPressMAX is a significant advancement in research tools and reagents for next-generation therapeutic discovery. By combining rapid, reliable protein expression with intelligent screening, we are helping our partners compress antibody discovery timelines without compromising quality."
Dr. Jie Zhang, Sino Biological’s General Manager, added: "AI is revolutionizing antibody screening, but it demands expression systems that can match its speed and throughput. XPressMAX achieves rapid, high-success expression of challenging proteins in as little as three hours."
The kit is available for researchers to explore at Sino Biological's product page, and a free sample can be requested here. Sino Biological is an international reagent supplier and CRO service provider specializing in recombinant protein production and antibody development, serving researchers in over 90 countries.
