Springs Rejuvenation has expanded its proprietary Stem 3 Protocol to five clinic locations across the United States, giving domestic patients direct access to a combination of peptide therapy, exosome treatment, and micro follicular unit extraction (micro FUE) hair restoration without the need to travel internationally. The expansion, led by Dr. Charles Pereyra MD, marks a structured rollout of services now available in New York City, Los Angeles, Austin, Miami, and Atlanta.
The Stem 3 Protocol, developed exclusively by Springs Rejuvenation, integrates three distinct modalities into a single treatment framework. Peptide therapy is used to support cellular signaling and recovery, exosome therapy delivers concentrated biological messengers to targeted tissue, and micro FUE hair restoration is performed using 0.9mm instrumentation—one of the smallest graft extraction tools used in clinical hair restoration today. The combination approach is designed to address hair loss, joint deterioration, and systemic recovery within a unified care model.
Springs Rejuvenation operates as a physician-led practice, meaning licensed medical doctors oversee all treatment planning and patient consultations at each location. The five-city footprint was established to reduce geographic barriers that have historically pushed patients toward offshore clinics in countries with less regulatory oversight.
For years, Americans seeking stem cell exosome therapy and advanced regenerative treatments often turned to clinics in Mexico, Panama, or Germany, where such protocols were more widely practiced. Springs Rejuvenation was built with the specific intent of changing that dynamic. Each of its five U.S. locations offers the full Stem 3 Protocol under the same clinical standards, allowing patients in different regions to receive consistent treatment without crossing borders.
"We now have five active clinic locations delivering the full Stem 3 Protocol, which means a patient in Atlanta has the same access as someone in New York or Los Angeles," said Dr. Charles Pereyra, MD, Founder and Medical Director of Springs Rejuvenation. "That consistency is what we built this network to achieve - Americans should not have to leave the country to access this level of regenerative care."
The practice also offers stem cell exosome therapy specifically for joint conditions, targeting patients dealing with cartilage wear, chronic inflammation, and mobility limitations. This service line runs parallel to the hair restoration program and is available across all five locations as part of the broader regenerative medicine offering.
Springs Rejuvenation maintains a physician-led model at every location, a structural decision that differentiates the practice from wellness centers or medical spas that offer similar terminology but without direct physician involvement. Dr. Charles Pereyra MD, a recognized regenerative medicine expert, established this standard as foundational to how each clinic operates, from intake through treatment completion.
The micro FUE component of the Stem 3 Protocol uses 0.9mm punch instrumentation, which minimizes scarring at the donor site and supports faster recovery compared to larger-gauge methods. When combined with exosome application post-extraction, the protocol is designed to improve graft survival rates and support follicular regeneration through biological signaling rather than mechanical intervention alone.
Patients interested in joint therapies receive exosome injections derived from ethically sourced biological material, administered directly into affected joints under physician supervision. The treatment is positioned as an option for individuals seeking alternatives to corticosteroid injections or surgical intervention, particularly those in earlier stages of joint degradation.
Learn more at Springs Rejuvenation.


