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Lifeasible Updates Yeast-Based Screening Platform to Accelerate Plant Resistance Gene Discovery

By Advos

TL;DR

Lifeasible's updated yeast-based screening platform gives researchers a competitive edge by rapidly identifying plant resistance genes to develop hardier, higher-yielding crops more efficiently.

Lifeasible's platform works by constructing yeast expression libraries from plant RNA, then screening clones under adverse conditions to identify and validate resistance genes through protein expression.

This technology helps create more resilient crops that can withstand environmental stresses, potentially improving food security and reducing agriculture's environmental impact for a better tomorrow.

Lifeasible uses yeast as a model organism to screen plant genes, offering a faster, more cost-effective alternative to traditional methods for discovering how plants resist toxins.

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Lifeasible Updates Yeast-Based Screening Platform to Accelerate Plant Resistance Gene Discovery

Lifeasible, a biotechnology company specializing in agricultural research, has announced an update to its yeast-based high-throughput screening platform designed to accelerate the discovery of plant genes that confer resistance to environmental stressors, pests, pathogens, and heavy metals. This development addresses growing agricultural challenges, including persistent heavy metal contamination in soil, disease attacks, and other environmental stresses that significantly impact plant growth, yield, and crop quality.

Traditional screening methods for identifying resistance genes are often slow, time-consuming, and limited in throughput, creating a need for faster and more cost-effective alternatives. Lifeasible's updated platform leverages yeast as a model system, which provides a viable alternative to animal models in toxicology and stress response studies, enabling high-throughput gene function analysis at reduced costs. The company's one-stop services now include construction of yeast expression libraries, isolation of RNA, construction of cDNA libraries, high-throughput screening for resistance genes, preparation of yeast working solutions, exploration of adverse conditions, screening of positive yeast clones under adverse conditions, gene identification of yeast positive clones, protein-induced expression and validation, phenotypic validation of yeast, knock out yeast strain creation and transformation, and complement (overexpression) verification.

"We are excited about the update of our yeast-based high-throughput screening platform. By combining the speed and flexibility of yeast genetics with a robust screening workflow, we are sure scientists will explore complex resistance mechanisms more efficiently, thus unlocking new possibilities in plant biotechnology and crop improvement," commented Isla, a representative speaker from Lifeasible. The company has years of experience in molecular biology and offers a wide range of services in plant biotechnology, including gene cloning, gene expression, modification, protein-protein or protein-DNA interactions, cell imaging, and phytochemical analysis to meet diversified research needs.

This update is important because it directly addresses critical bottlenecks in agricultural research and development. With climate change, soil degradation, and increasing pest pressures threatening global food security, the ability to rapidly identify resistance genes can accelerate the development of hardier crop varieties. This has implications for farmers facing yield losses, consumers concerned about food availability and safety, and industries reliant on agricultural raw materials. More efficient gene discovery could lead to crops that require fewer chemical inputs, are more resilient to environmental challenges, and contribute to sustainable agriculture practices. For more detailed information about the updated yeast-based high-throughput screening for resistance genes, visit https://www.lifeasible.com/custom-solutions/plant/analytical-services/high-throughput-screening-for-resistance-genes-using-yeast/.

Curated from 24-7 Press Release

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