Creative Biogene Launches Comprehensive Custom RNA Services to Accelerate Research and Therapeutic Development

Creative Biogene has announced the release of its custom RNA services, establishing a foundation for transforming cutting-edge scientific discoveries into industry-grade tools and service capabilities. This development comes as RNA has evolved from a research subject to a key element in drug development and therapeutic applications, with technologies like mRNA vaccines, circular RNA, and self-amplifying RNA driving unprecedented demand for customized solutions.

The company offers a comprehensive range of custom RNA services including the synthesis and customization of mRNA, saRNA, circRNA, and RNA interference molecules. Their expert team, composed of experienced scientists in RNA research, is dedicated to meeting the unique needs of researchers across various fields from academic laboratories to pharmaceutical companies. Creative Biogene's strength lies in rigorous quality control measures that ensure purity, functionality, and batch-to-batch consistency to meet industry standards.

The core of Creative Biogene's custom RNA services relies on advanced engineering capabilities that enable sophisticated modifications to RNA molecules. These modifications include introducing specific nucleotides and optimizing structural features to enhance stability and efficacy for diverse experimental and clinical uses. The service offers high flexibility with production scales ranging from micrograms to grams, accommodating both basic research and large-scale therapeutic applications.

Specialized support for miRNA and circRNA research includes precise sequence design and expression profiling of miRNAs to elucidate their roles in gene regulation and disease progression. The service also provides efficient synthesis and functional analysis of circRNAs to deepen understanding of their dynamic changes and therapeutic potential. The launch also marks the establishment of Creative Biogene's one-stop Contract Development and Manufacturing Organization platform, which integrates all stages of RNA drug development from sequence design and in vitro transcription to GMP-grade manufacturing and validation.

CDMO services encompass comprehensive analytical services for assessing RNA integrity and ensuring compliance with stringent regulatory requirements. The introduction of lipid nanoparticle encapsulation technology represents a significant advancement in therapeutic drug delivery, enabling efficient multi-component co-encapsulation to meet diverse therapeutic needs. According to Marcia Brady, marketing director of Creative Biogene, the company is committed to becoming a leader in the RNA services market through extensive expertise in molecular biology, RNA chemistry, and drug development. The company provides tools to translate experimental discoveries into practical applications based on rigorous scientific principles and operational excellence.